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Late Onset Postpartum Eclampsia Without Pre-Eclamptic Prodromi: Clinical and Neuroradiological Presentation in Two Patients
JNNP 69:824-827, Veltkamp,R.,et al, 2000
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Article Abstract
In two patients eclampsia started 9 days postpartum. Headache and visual disturbances preceded seizures but none of the classic pre-eclamptic signs oedema, proteinuria, and hypertension were present until shortly before seizure onset. Brai n herniation (patient 1) and status epilepticus (patient 2) necessitated neurointensive care management. Brain MRI initially showed only frontal sulcal effacement in one patient but later showed white matter hyperintensities on T2 weighted images and a p reviously undescribed pattern of cortical-subcortical postgadolinium enhancement on T1 weighted images in both. Neurological deficits and MRI findings were reversed with therapy in both patients. It is concluded that late postpartum eclampsia can manife st without classic prodromi and that characteristic MRI findings may lag behind clinical manifestation.
 
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cerebral cortex
eclampsia
eclampsia,postpartum
gadolinium
gray matter
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MRI,cortical enhancement
MRI,gray matter enhancement
postpartum
pregnancy,neurologic complications in
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